Histopathology
| 1. Lichen Planus |
| Section show laminated hyperkeratosis with irregular acanthosis of the epidermis. The retepegs are elongated and pointed giving a saw toothed appearance to the section.Wedge shaped hypergranulosis is present and there is marked degeneration of the basal layer with presence of several civatte bodies at the dermo-epidermal junction.A band like infiltrate of lymphocytes and histiocytes is presene in the superficial dermis aborting to the epidermis. |
| 2. Lichen Planus Hypertrophicus. |
| Section shows laminated hyperkeratosis with patchy parakeratosis and marked keratotic plugging.The epidermis is irregularly acanthotic with elongated thickened, bulbous retepegs. There is wedge shaped hypergranulosis seen and patchy degeneration of the basal cell layer is present. A band like infiltrate of lymphocytes and histiocytes is seen in the superficial dermis aborting on to the epidermis at places. |
| 3. Becker Nevus |
| Section shows mild basket weave ,hyperkeratosis, the epidermis is acanthotic with downward extension and branching of the rete pegs. The granular layer is present throughout and basal cell layer is intact with focal hyperpigmentation specially at the lower most end of the rete pegs. The dermis shows no pathology. |
| 4. Intradermal Nevus |
| Section shows mild laminated hyperkeratosis with atrophy of the epidermis. The rete peg pattern is well maintained. Basal cell layer is intact with normal pigmentation. No functional activity seen. Dermis shows presence of tumor tissue composed of nests and cords of proliferating melanocytes. Nests of cells in the superficial dermis are round with central nuclei and abundant melanin pigment. The tumor cells in the deeper dermis are spindle shaped arranged in bundles simulating nerve fibres. No atypical changes seen. |
| 5. Sweet Syndrome |
| Section shows mild basket weave hyperkeratosis with irregular acanthosis of the epidermis. The basal cell layer is intact with normal pigmentation. A sub-epidermal bulla is present which shows fibrin strands with few neutrophils. The base of the bulla is formed by the dermis that shows a band like infiltrate of neutrophils with few lymphocytes and histiocytes. There is marked superficial edema with dialatation and congestion of blood vessels. |
| 6. Schamberg’s disease |
| Section shows laminated hyperkeratosis with karatotic plugging. The epidermis is atrophic and shows a complete flattening of the rete pegs. The granular layer is present throughout and the basal cell layer is intact with normal pigmentation. A band like infiltrate of lymphocytes and histiocytes is present in the superficial dermis. Perl’s stain is positive for iron deposition. |
| 7. Milia |
| Section shows laminated hyperkeratosis overlying an epidermis that shows patchy atrophy. There are several cystic structures present that are arising from the lower portion of the infundibulum of the vellus hairs. The cysts are lined by stratified epithelium and contain concentric ring of keratin. A sparse perivascular lymphocytes is present in the surrounding blood vessels. |
| 8. Basal Cell Carcinoma |
| Section shows mild basket weave pattern of stratum corneum with follicular plugging . the epidermis is atrophic with flattening of rete pegs. The dermis shows presence of tumor tissues present in lobules that are surrounded by proliferating fibroblasts. Tumor cells have a monomorphic appearance and shows large hyperchromatic nuclei surrounded by thin rim of cytoplasm. Palisading mass present in the groups of tumor cells among which some shows central keratinisation. |
| 9. Epidermoid cyst |
| 10. BL |
| 11. LD Bodies |
| 12. BT |
| 13. Morphea |
| Section shows mild basket weave hyperkeratosis. The epidermis is normal in appearance and has a well defined rete peg pattern. Basal cell layer is intact and shows normal pigmentation. There is thickening and hyalinization of the dermal collagen, together with a perivascular lympho-hystiocytic infiltrate seen in the superficial dermis. The sweat glands are atrophic and seem to be “pulled up: into the dermis. VVG stain shows normal elastic fibers. |
| 14. FF |
| 15. Spongiotide |
| 16. Pigmented Seborrhoeic Keratosis |
| 17. Pitryiasis Lichenoides |
| 18. lichen planus |
| 19. Histoid leprosy |
| Section shows laminated hyperkeratosis overlying a mildly atrophic epidermis. There is flattening of rete pegs but the basal layer is intact with normal pigmentation. A free grenz zone is present beneath which the dermis shows infilteration by foamy histiocytes and few lymphocytes. The histiocytes at places show spindled out appearance and there is evidence of nerve infilteration. FF stain is positive for AFB. |
| 20. Sarcoidosis |
| 21. L set at |
| 22. Syringoma |
| Section shows basket weave pattern of stratum corneum overlying a normal epidermis with well defined rete peg pattern. Basal layer is intact and shows normal pigmentation. The dermis shows the presence of tumor tissue that is made up of several tubular structures embedded in a fibrous stroma. These ducts are lined by two rows of epithelial cells with the inner layer showing marked vacuolization. Amorphous material is present in some of these ducts that also posses a small comma like. |
| 23. lupus vulgaris |
| 24. Tricholemmal cyst |
| 25. Squamous cell carcinoma |
| Section shows hyperkeratotic acanthotic stratified squamous epithelium. The underlying subepithelial tissue shows the presence of groups and nests of malignant squamous cells infilterating up to and into the muscle layers. The cells are large with central hyperchromatic nuclei and there are areas of keratinization seen with formation of squamous perls. Few mitotic figures are present and the surrounding connective tissue is heavily infilterated by lymphocytes, histiocytes, eosinophils and few neutrophils. |
| 26. Postular psoriasis |
| 27. Lymphangioma |
| 28. Spongiotic Postule of Kojog |
| 29. Psoriasis |
| Section shows hyperparakeratosis with general aggregates of neutrophils forming numerous abscesses. The epidermis is acanthotic and has narrow elongated rete pegs. Marked hypogranulosis is seen but basal cell layer is intact and shows normal pigmentation. There is papillary edema and thinning of the suprapapillary epidermal plates. Thin walled congested blood vessels are present in dermal papillae and an perivascular lymphohistiocyic infilteration is present in superficial dermis. |
| 30. Bullous pemphigoid |
| 31. Pityriasis lichenoides Chronicus |
| 32. Discoid lupus erythematosus |
| 33. Keloid |
| 34. SCLE |
